STUDY SHOWS HIGH-DOSE VITAMIN E SUPPLEMENTS MAY INCREASE RISK OF DYING
This was published in two highly-respected peer-reviewed journals, made national news, and led to much public discussion. (i.e. News bulletins on all stations warning, “Stop taking vitamin E as a major study shows that it increases the incidence of heart disease, cancer, and many other conditions.”)
Then a scientist from Harvard shot it down with the statement, “What that study really showed was that people who are suffering from critical diseases are more likely to take vitamin E.”
Reference:
https://www.quora.com/What-are-some-of-the-worst-academic-papers-ever-published